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miRNA-Microbiota Interaction in Gut Homeostasis and Colorectal Cancer
Jiayi Dong1, Jesse W Tai1, Li-Fan Lu2
1Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Trends in Cancer
|November 19, 2019
Abstract:
Gut homeostasis is maintained by dynamic host-microbiota interactions. Recently, miRNAs have emerged as key molecular regulators in the mediation of such interactions. Here, we discuss the role of a host miRNA-microbiome axis in gut homeostasis and colorectal cancer (CRC) and the involvement of diet and microbial metabolites in miRNA-mediated intestinal health.
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