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Updated: Jan 3, 2026
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Immunological biomarkers in severe asthma
Dharani Narendra1, John Blixt1, Nicola A Hanania1
1Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, Texas, United States.
Abstract:
Severe asthma is heterogeneous in its clinical presentation, underlying pathophysiology, course and response to therapy. Clinical and physiological assessment of severe asthma is often inadequate in predicting underlying disease mechanisms and or response to medications. With the emergence of novel targeted therapies in severe asthma, the need for reproducible, easily measured biomarkers became obvious but only few are currently available for clinical use. These biomarkers along with the clinical presentation of the patient play an important role in identifying phenotypes and endotypes, predicting the clinical course and prognosis and improving the precision therapeutic approach to asthma.
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