Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

572
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
572
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

2.3K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.3K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

468
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
468
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

961
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
961
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

695
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
695
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

765
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
765

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Indications, techniques, and safety of cryotherapy and cryobiopsy via flexible bronchoscopy in pediatric patients.

Annals of the American Thoracic Society·2026
Same author

Endobronchial Lesions in Children: Radiologic, Bronchoscopic, and Pathologic Correlation.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same author

Endoscopic tracheoesophageal fistula closure-Electrocautery combined with esophageal clip application in pediatric patients.

Journal of pediatric gastroenterology and nutrition·2026
Same author

Lower Respiratory Tract Bacterial Profiles Are Associated With Respiratory Severity and Bronchopulmonary Dysplasia in Neonates.

Pediatric pulmonology·2025
Same author

In Response to A Clinical Consensus Statement on Pulmonary Recurrent Respiratory Papillomatosis.

The Laryngoscope·2025
Same author

Endobronchial valves for severe air leak in critically ill children with necrotizing pneumonia requiring extracorporeal membrane oxygenation.

Perfusion·2025
Same journal

Strategies for prevention of intraventricular hemorrhage in the neonatal intensive care unit.

Seminars in fetal & neonatal medicine·2026
Same journal

Introduction.

Seminars in fetal & neonatal medicine·2026
Same journal

Introduction.

Seminars in fetal & neonatal medicine·2026
Same journal

Should inhaled nitric oxide be used for respiratory failure in preterm infants?

Seminars in fetal & neonatal medicine·2026
Same journal

Inhaled nitric oxide in premature infants for respiratory failure: Discussion and consensus.

Seminars in fetal & neonatal medicine·2026
Same journal

Critical thinking in red blood cell transfusion decisions: Donor, product, recipient, and outcomes.

Seminars in fetal & neonatal medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 3, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.8K

Chronic ventilator dependence in infants

Joseph Piccione1, Alexiou Stamatia1

  • 1Division of Pulmonary Medicine, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Seminars in Fetal & Neonatal Medicine
|November 19, 2019
PubMed
Summary

No abstract available in PubMed .

More Related Videos

A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

420
3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

923

Related Experiment Videos

Last Updated: Jan 3, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.8K
A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

420
3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

923