Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

551
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
551
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

499
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
499
Acute Pharyngitis01:30

Acute Pharyngitis

3.6K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
3.6K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

404
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
404
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

249
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
249
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

375
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
375

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decreased IgE-binding with Wheat Gluten by Deamidation.

Bioscience, biotechnology, and biochemistry·2016
Same author

In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations.

Stroke·2001
Same author

Compound heterozygous mutations (PHE53/54DEL and HIS373LEU) of the P450c17 gene result in a 17alpha-hydroxylase/17,20-lyase deficient male pseudohermaphrodite with unambiguous external genitalia.

The Tohoku journal of experimental medicine·2000
Same author

Inhaled furosemide greatly alleviates the sensation of experimentally induced dyspnea.

American journal of respiratory and critical care medicine·2000
Same author

Osteosarcomatosis involving craniofacial bones presenting with cranial nerve palsies.

The Journal of laryngology and otology·2000
Same author

Effects of oral administration of "rumen-bypass" vitamin D3 on vitamin D and calcium metabolism in periparturient cows.

The Journal of veterinary medical science·2000

Related Experiment Video

Updated: Jan 3, 2026

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

10.9K

Pyogenic spondylitis with acute course caused by Corynebacterium simulans.

M Ogasawara1, T Matsuhisa1, T Kondo2

  • 1Department of General Medicine, Nagoya University Hospital, Tsurumai-cho 65, Showa-ku, Nagoya, Aichi, 466-8560, Japan.

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|November 19, 2019
PubMed
Summary

This study reports the first case of acute pyogenic spondylitis caused by Corynebacterium simulans, a bacterium typically found on skin. The patient recovered after antibiotic treatment, highlighting a rare but serious infection presentation.

Keywords:
Acute courseCorynebacterium simulansDiabetes mellitusSpondylitisVancomycin

More Related Videos

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

5.3K
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.5K

Related Experiment Videos

Last Updated: Jan 3, 2026

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

10.9K
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

5.3K
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.5K

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Spinal Infections

Background:

  • Corynebacterium simulans is a commensal bacterium of human skin flora, identified in 2000.
  • Infections by Corynebacterium species are uncommon, with pyogenic spondylitis being a rare manifestation.
  • Pyogenic spondylitis caused by C. simulans has not been previously documented in medical literature.

Observation:

  • A 78-year-old male patient with diabetes mellitus presented with acute lower back pain and fever.
  • Blood cultures identified Corynebacterium simulans as the causative agent.
  • Magnetic resonance imaging confirmed acute pyogenic spondylitis of the lumbar vertebrae.

Findings:

  • This case represents the first documented instance of acute pyogenic spondylitis caused by Corynebacterium simulans.
  • Unlike the typically chronic course of Corynebacterium-induced spondylitis, this infection presented acutely.
  • The patient achieved a full recovery after a 9-week course of vancomycin treatment.

Implications:

  • This case expands the spectrum of clinical manifestations associated with Corynebacterium simulans.
  • It underscores the importance of considering less common pathogens in pyogenic spondylitis, even those part of normal flora.
  • Highlights the potential for acute presentations of spondylitis by skin commensals, necessitating prompt diagnosis and treatment.