Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

History of Microbiology01:28

History of Microbiology

7.0K
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
7.0K
Heritability01:06

Heritability

541
Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic"...
541
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

523
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
523
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

450
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
450
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

893
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
893
Mutations in Microorganisms01:18

Mutations in Microorganisms

455
Mutations are heritable changes in an organism’s genome involving alterations in the base sequence of DNA or RNA. These changes can influence cellular processes and phenotypic traits, potentially transforming the unaltered wild type into a mutant form. Such changes, termed forward mutations, are pivotal in shaping the genetic diversity of organisms.RNA viruses exhibit the highest mutation rates due to the absence of robust proofreading mechanisms during genome replication. In contrast,...
455

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole-genome resequencing reveals signatures of selection and timing of duck domestication.

GigaScience·2018
Same author

Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats.

Molecular medicine reports·2018
Same author

A cell viability assessment method based on area-normalized impedance spectrum (ANIS).

Biosensors & bioelectronics·2018
Same author

Diffuse Myocardial Injuries are Present in Subclinical Hypothyroidism: A Clinical Study Using Myocardial T1-mapping Quantification.

Scientific reports·2018
Same author

Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma.

International journal of medical sciences·2018
Same author

Antitumor activity of the <i>Ailanthus altissima</i> bark phytochemical ailanthone against breast cancer MCF-7 cells.

Oncology letters·2018

Related Experiment Video

Updated: Jan 3, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

31.0K

[The concepts and research progress: from heritability to microbiability].

Chao Liang Wen1, Cong Jiao Sun1, Ning Yang1

  • 1National Engineering Laboratory for Animal Breeding, College of Animal Science andTechnology, China Agricultural University, Beijing100193, China.

Yi Chuan = Hereditas
|November 19, 2019
PubMed
Summary
This summary is machine-generated.

Heritability quantifies genetic variation for traits. Microbiability (m 2) extends this concept to the gut microbiome, assessing its influence on host phenotypes.

More Related Videos

A Method for Targeted 16S Sequencing of Human Milk Samples
09:09

A Method for Targeted 16S Sequencing of Human Milk Samples

Published on: March 23, 2018

10.2K
A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
08:14

A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model

Published on: February 28, 2018

9.2K

Related Experiment Videos

Last Updated: Jan 3, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

31.0K
A Method for Targeted 16S Sequencing of Human Milk Samples
09:09

A Method for Targeted 16S Sequencing of Human Milk Samples

Published on: March 23, 2018

10.2K
A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
08:14

A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model

Published on: February 28, 2018

9.2K

Area of Science:

  • Quantitative genetics
  • Microbiome research
  • Host-microbe interactions

Background:

  • Heritability is crucial for understanding trait variation in evolution, agriculture, and medicine.
  • Statistical methods for heritability estimation have evolved significantly since 1918.
  • The gut microbiome's role in host phenotypes is an emerging area of study.

Purpose of the Study:

  • To review advancements in statistical methods for heritability estimation.
  • To explore the current understanding of gut microbiome associations with the host genome.
  • To focus on the concept and estimation methods of microbiability (m 2).

Main Methods:

  • Literature review of statistical genetics and microbiome research.
  • Synthesis of existing methodologies for heritability and microbiability estimation.
  • Analysis of host genome-microbiome-phenotype relationships.

Main Results:

  • Progress in statistical models for heritability has been substantial.
  • Microbiability (m 2) offers a novel framework to quantify microbial contributions to host traits.
  • The review highlights the interplay between host genetics and the gut microbiome.

Conclusions:

  • Microbiability (m 2) is a valuable tool for dissecting host phenotypic variation.
  • Future research should leverage microbiability to understand host-microbiome-genotype interactions.
  • This review serves as a reference for advancing host phenotypic variation studies.