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CT of intracranial tuberculomas with specific reference to the "target sign"
1Department of Radiology, Faculty of Medicine, University of the Orange Free State, Bioemfontein, Republic of South Africa.
Abstract:
The CT appearances of 30 patients with a total of 58 intracranial tuberculomas are discussed. Of specific interest in this study is the relatively high incidence of patients who presented with the target sign. To date there has been only 1 report of 4 cases with this appearance on CT. Four basic patterns of post contrast enhancement are described. As suggested by Welchman this study concludes that the target sign is pathognomonic of an intracranial tuberculoma.
Insights
The target sign on CT scans is a key indicator for diagnosing intracranial tuberculomas. This study highlights its high incidence, suggesting it is pathognomonic for this condition.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Intracranial tuberculomas are a form of extrapulmonary tuberculosis.
- Accurate diagnosis is crucial for effective treatment.
Purpose of the Study:
- To analyze the CT appearances of intracranial tuberculomas.
- To investigate the diagnostic significance of the 'target sign'.
Main Methods:
- Retrospective review of CT scans from 30 patients with 58 intracranial tuberculomas.
- Analysis of contrast enhancement patterns.
Main Results:
- A relatively high incidence of the 'target sign' was observed.
- Four basic patterns of post-contrast enhancement were identified.
- The 'target sign' was present in a significant number of cases.
Conclusions:
- The 'target sign' on CT is pathognomonic for intracranial tuberculoma.
- This finding aids in the specific diagnosis of neurotuberculosis.