Case report: Malignant-type calcification of the nipple with histologic correlation
Related Experiment Video
Updated: Jan 3, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
1Breast Unit-Out patient Department, Hung Vuong Hospital, 128 Hong Bang Street, Ward 12, District 5, Ho Chi Minh city, Vietnam.
Abstract:
Malignant-type calcification of the nipple is a rare lesion, with only 2 cases reported in literature. We present a case of a 48-year-old female who came to us because of noncycle breast pain, where malignant-type calcification of the nipple was incidentally seen on mammography. The final pathology is fibrocystic change with benign calcium in connective tissue. Different diagnosis of malignant and benign histology of malignant-type calcification with no associated mass is difficult or even not eligible so that wedge excision the nipple without making the deformity needs to perform to diagnose the histology.

