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Case report: Malignant-type calcification of the nipple with histologic correlation
1Breast Unit-Out patient Department, Hung Vuong Hospital, 128 Hong Bang Street, Ward 12, District 5, Ho Chi Minh city, Vietnam.
Radiology Case Reports
|November 19, 2019
Summary
Malignant-type calcification of the nipple, a rare finding, can be challenging to diagnose. This case highlights that such calcifications may represent benign fibrocystic changes, necessitating surgical evaluation for definitive diagnosis.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Malignant-type calcification of the nipple is an exceptionally rare breast lesion, with limited documented cases.
- Differentiating benign from malignant histology of nipple calcifications without an associated mass presents diagnostic challenges.
Observation:
- A 48-year-old female presented with noncyclic breast pain.
- Mammography incidentally revealed malignant-type calcification of the nipple.
- Histopathological examination confirmed fibrocystic change with benign calcium deposits.
Findings:
- The study presents a case where malignant-type nipple calcification was found to be benign fibrocystic change.
- Accurate histological diagnosis of nipple calcifications without a mass is difficult, often requiring surgical intervention.
Implications:
- This case underscores the importance of considering benign etiologies for malignant-appearing nipple calcifications.
- Wedge excision of the nipple may be necessary for definitive histological diagnosis to avoid unnecessary deformity.
- Further research into non-invasive diagnostic methods for nipple calcifications is warranted.
