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Tufted angioma presenting with subclinical coagulopathy
Sean Cohen, Kathryn L Anderson1, Omar P Sangueza
1Department of Dermatology, Wake Forest Baptist Medical Center, Winston Salem, NC. klanders@wakehealth.edu.
Dermatology Online Journal
|November 19, 2019
Summary
Tufted angioma, a rare vascular tumor, can present with coagulopathy even without Kasabach-Merritt phenomenon. Early laboratory workup is crucial for asymptomatic cases to detect potential bleeding risks.
Area of Science:
- Dermatology
- Hematology
- Pediatric Oncology
Background:
- Tufted angioma is a rare, benign vascular tumor.
- Kasabach-Merritt phenomenon (KMP) is a serious coagulopathy associated with tufted angioma, causing low platelets and fibrinogen.
- KMP occurs in about 10% of tufted angioma cases.
Observation:
- A 10-month-old boy presented with an erythematous patch.
- Biopsy confirmed tufted angioma.
- Baseline labs showed mild fibrinogen decrease and elevated D-dimer, without thrombocytopenia or PTT changes.
Findings:
- Asymptomatic tufted angioma can present with coagulopathy.
- Coagulopathy may occur independently of Kasabach-Merritt phenomenon.
- Subtle hemostatic abnormalities are detectable in early stages.
Implications:
- Routine laboratory workup is essential for all tufted angioma patients.
- Early detection of coagulopathy aids in timely management.
- This finding expands understanding of tufted angioma-associated bleeding risks.
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