Systemic contact dermatitis related to alcoholic beverage consumption

Area of Science:

• Dermatology
• Allergology
• Toxicology

Background:

• Systemic contact dermatitis (SCD) is a widespread rash resulting from systemic allergen exposure.
• Balsam of Peru, a plant extract used in fragrances and flavors, is a known allergen.
• Alcoholic beverages may contain various allergens, including Balsam of Peru.

Observation:

• Two patients presented with recurrent, diffuse, erythematous, and pruritic skin rashes.
• Clinical history, physical examination, and patch testing were performed.
• The patients' symptoms were suggestive of contact dermatitis.

Findings:

• Patch testing confirmed hypersensitivity to Balsam of Peru in both patients.
• The likely cause of the systemic contact dermatitis was Balsam of Peru in their alcoholic beverages.
• Both patients experienced marked improvement after discontinuing alcohol consumption.

Implications:

• This case highlights a rare cause of systemic contact dermatitis linked to alcohol consumption.
• Balsam of Peru is a frequent allergen, and its presence in alcoholic beverages should be considered.
• Increased clinical suspicion is necessary to identify allergens like Balsam of Peru in alcoholic drinks, including artificial flavorings and aromas.