Related Experiment Video
Updated: Jan 3, 2026
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Nasal glial heterotopia in children: Two case reports and literature review
Yang-Yan Yan1, Zhi-Ying Zhou1, Jing Bi1
1Department of Otorhinolaryngology, Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Hangzhou, China.
Insights
Nasal glial heterotopia, a rare birth defect, presents with nasal congestion. This condition, though rare, is successfully treated in children with a low recurrence rate, indicating a good prognosis.
Area of Science:
- Developmental Biology
- Pediatric Otolaryngology
- Medical Imaging
Background:
- Nasal glial heterotopia is an uncommon congenital malformation involving misplaced glial tissue in the nasal region.
- Understanding its presentation and management is crucial for pediatric care.
Observation:
- Two pediatric cases of nasal glial heterotopia are detailed, including symptoms, imaging, and histology.
- A comprehensive literature review identified 60 pediatric cases from 1980-2018.
Findings:
- The primary symptoms observed were nasal congestion and open-mouth breathing.
- All identified pediatric patients achieved successful treatment outcomes.
- The recurrence rate for nasal glial heterotopia was notably low at 5%.
Implications:
- Multidisciplinary management is recommended for optimal outcomes in nasal glial heterotopia.
- Despite its rarity, nasal glial heterotopia demonstrates a favorable prognosis with appropriate intervention.
- This review highlights key aspects of pediatric nasal glial heterotopia for clinical awareness.
Abstract:
Nasal glial heterotopia is a rare developmental anomaly. We present two cases of nasal glial heterotopia. The presenting symptoms, imaging findings, treatment, histological appearance, and follow-up are described in detail. We additionally reviewed all pediatric cases of nasal glial heterotopia published between 1980 and 2018 in the PubMed and Baidu Scholar databases. We identified 60 pediatric patients (36 [60%] boys). The main symptoms were nasal congestion and open-mouth breathing. Treatment was successful in all patients, and the recurrence rate was low (3/60, 5%). Nasal glial heterotopia requires multidisciplinary management but has a good prognosis.
