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Related Concept Videos

Dose-Response Relationship: Selectivity and Specificity01:25

Dose-Response Relationship: Selectivity and Specificity

Drugs exert their therapeutic effects by interacting with receptors, enzymes, or ion channels that are present throughout the human body. The strength and duration of the interaction between a drug and its target receptor are characterized by the selectivity and specificity of the drug. Selectivity refers to a drug's strong preference for its intended target over other targets. For instance, isoprenaline, a non-selective β-adrenergic agonist, interacts with both β1- and β2-adrenergic receptors...

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The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice
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Response to Rubanovich et al

R Z Hayeems1,2, S Luca3, W J Ungar3,4

  • 1Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada. robin.hayeems@sickkids.ca.

Genetics in Medicine : Official Journal of the American College of Medical Genetics
|November 20, 2019
PubMed
Summary

No abstract available in PubMed .

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