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Intellectual Disability01:29

Intellectual Disability

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Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
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Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Intellectual functioning in alpha-mannosidosis.

Sara S Cathey1, Sara M Sarasua1,2, Richard Simensen1

  • 1Greenwood Genetic Center Greenwood South Carolina.

JIMD Reports
|November 20, 2019
PubMed
Summary

Alpha-mannosidosis patients exhibit intellectual disability that worsens with age. Hematopoietic stem cell transplantation may stabilize cognitive abilities in individuals with this rare metabolic disorder.

Failed At:

2026-06-19T13:38:25.108317+00:00

Keywords:
IQalpha‐mannosidosisglycoproteinosesintellectual disability

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