Related Experiment Video
Updated: Jan 3, 2026

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
Published on: March 17, 2023
Association of leukemia and mitochondrial diseases-A review
Ashwani Sachdeva1, Jagadish Prasad Rajguru2, Kanwardeep Sohi3
1Department of Prosthodontics, J.C.D Dental College, Sirsa, Haryana, India.
Abstract:
Mitochondria play an important role in various metabolic pathways like oxidative phosphorylation free radical generation and apoptosis. Defects in mitochondrial function are responsible for a number of heterogenous clinical presentations along with development and progression of cancer. Decrease in cellular energy (ATP) production because of impaired oxidative phosphorylation is the most important cause for these underlying disorders. The present review article aims to provide current understanding of mitochondrial genetics and biology and relates the mt-DNA alterations in leukemia patients.
More Related Videos
09:44Flow Cytometric Analysis of Mitochondrial Reactive Oxygen Species in Murine Hematopoietic Stem and Progenitor Cells and MLL-AF9 Driven Leukemia
Published on: September 5, 2019
03:57Assessment of Mitochondrial Oxygen Consumption Using a Plate Reader-based Fluorescent Assay
Published on: April 12, 2024
Related Concept Videos
Electron Transport Chain: Complex I and II
ROS generation is regulated and maintained at moderate levels necessary...
Mitochondrial Membranes
ATP Synthase: Structure
Animal Mitochondrial Genetics
Mitochondria