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Restricting high-end antibiotics usage - challenge accepted!

J Jayalakshmi1, M S Priyadharshini1

  • 1Department of Microbiology, P.S.G. Institute of Medical, Sciences and Research, Coimbatore, Tamil Nadu, India.

Journal of Family Medicine and Primary Care
|November 20, 2019
PubMed
Abstract

Insights

Judicious use of high-end antibiotics improved significantly after educational interventions, reducing unjustified prescriptions by 51.2%. This highlights the importance of antimicrobial stewardship for better patient outcomes and combating resistance.

Area of Science:

  • Infectious Diseases
  • Clinical Pharmacy
  • Hospital Administration

Background:

  • Antimicrobial resistance (AMR) poses a significant threat, increasing morbidity, mortality, and healthcare costs.
  • The misuse of antimicrobials accelerates the development of AMR.
  • Antimicrobial stewardship programs, including preauthorization and restricted use of high-end antibiotics, are crucial for managing AMR.

Purpose of the Study:

  • To assess the judicious usage of high-end antibiotics in hospitalized patients.
  • To evaluate the impact of educational interventions on antibiotic prescribing practices.

Main Methods:

  • A prospective observational study was conducted over three months.
  • Data on high-end antibiotic usage were collected using a structured proforma.
  • Department-wise educational interventions and feedback were provided, followed by reassessment.

Main Results:

  • Meropenem was the most frequently used high-end antibiotic.
  • Educational interventions led to a 51.2% reduction in unjustified antibiotic usage.
  • The appropriateness of antibiotic usage increased from 77% pre-intervention to 88% post-intervention.

Conclusions:

  • Sustained compliance with judicious high-end antibiotic use is essential.
  • Continuous strengthening of antimicrobial stewardship practices is critical for combating AMR.
Keywords:
Antibioticsantimicrobial resistanceantimicrobial stewardshipauditrestricted antibiotics usage

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