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Vascular liver calcification in infants. A case report with some pathogenetic considerations
1Department of Paediatric Radiology, Ospedale Infantile, Alessandria, Italy.
Pediatric Radiology
|January 1, 1988
Summary
This case study describes calcified portal vein thromboemboli in a neonate, highlighting its radiological and histological features. A potential cause is disseminated intravascular coagulation triggered by placental thromboplastin release.
Area of Science:
- Neonatal medicine
- Vascular pathology
- Radiology
Background:
- Portal vein thromboembolism (PVT) is rare in neonates.
- Calcification of PVT is an even rarer finding.
- Understanding the pathogenesis is crucial for diagnosis and management.
Observation:
- A neonate presented with findings suggestive of portal vein thromboemboli.
- Radiological imaging revealed calcified thrombi within the portal vein.
- Histological examination confirmed the presence of calcified thromboemboli.
Findings:
- The case details the specific radiological and histological characteristics of calcified portal vein thromboemboli.
- A proposed pathogenetic mechanism involves disseminated intravascular coagulation (DIC).
- This DIC is hypothesized to be secondary to thromboplastin release from the placenta.
Implications:
- This case expands the understanding of PVT presentations in neonates.
- It highlights the importance of considering DIC in neonates with unexplained thromboembolism.
- Radiological and histological correlation is key for diagnosing rare vascular conditions.