Related Experiment Video
Updated: Jan 3, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
Ophthalmic adverse effects of lithium
John S Y Park1, Rahul A Sharma1, Verinder Sharma2
1Department of Ophthalmology, The Ottawa Eye Institute, University of Ottawa, Ottawa.
Lithium, a key bipolar disorder treatment, can cause eye problems like dry eye and abnormal vision. Understanding these ophthalmic side effects is crucial for patient compliance and effective management.
Area of Science:
- Ophthalmology
- Psychiatry
- Pharmacology
Background:
- Lithium is a primary treatment for bipolar disorders.
- Its side effects are well-documented but can be challenging.
- Ophthalmic side effects of lithium are less understood, potentially impacting treatment adherence.
Purpose of the Study:
- To review and summarize the ophthalmic adverse effects of lithium.
- To highlight the importance of recognizing and managing these ocular side effects.
Main Methods:
- Extensive literature review on lithium and its ophthalmic adverse effects.
Main Results:
- Documented ophthalmic adverse effects include exophthalmos, abnormal eye movements, ocular myasthenia gravis, papilledema, photophobia, and abnormal tear film leading to dry eye disease.
Conclusions:
- Ophthalmic side effects of lithium are diverse and require greater recognition.
- Further research is needed to fully understand lithium's impact on ocular structures.
- Interprofessional collaboration between psychiatrists and ophthalmologists is vital for optimal patient care.
Related Concept Videos
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Mania and Antimanic Drugs: Overview
Photoreceptors and Visual Pathways
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Accessory Structures of the Eye

