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A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation.

M Ilcim Thestrup1, Sara Caviglia1, Jordi Cayuso2

  • 1University of Copenhagen, NNF Center for Stem Cell Biology (DanStem), Blegdamsvej 3B, 2200, Copenhagen N, Denmark.

Nature Communications
|November 21, 2019
PubMed
Summary

The study reveals how the hepatopancreatic ductal system forms in zebrafish. EphB/EphrinB signaling is crucial for remodeling nascent lumens into functional ducts, ensuring bile and enzyme transport.

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