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Updated: Jan 3, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Published on: September 26, 2013

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IL-17 receptor-based signaling and implications for disease

Xiaoxia Li1, Rami Bechara2, Junjie Zhao3

  • 1Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. lix@ccf.org.

Nature Immunology
|November 21, 2019
PubMed
Summary

Interleukin-17 (IL-17) signaling is complex, with new discoveries explaining its potent in vivo functions in inflammation, immunity, and cancer. Understanding IL-17's molecular mechanisms bridges the gap between cell culture and its diverse physiological roles.

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