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Published on: March 14, 2017
Treatment of hypercalcaemia in thyrotoxicosis with aminohydroxypropylidene diphosphonate
T T Tan1, A A Alzaid, N Sutcliffe
1University Department of Medicine, Royal Infirmary, Glasgow, UK.
Abstract:
Two patients had symptomatic hypercalcaemia accompanying thyrotoxicosis, despite initial treatment with volume repletion, beta blockade and antithyroid drugs. They were further managed with intravenous infusions of aminohydroxypropylidene diphosphonate resulting in rapid normalization of the serum calcium, with relief of symptoms. Aminohydroxypropylidene diphosphonate effectively suppressed the increased bone resorption of thyrotoxicosis without any undesirable adverse effects.
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