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Quality of life of chronic heart failure patients: a systematic review and meta-analysis

Mandana Moradi1, Fereshteh Daneshi2, Razieh Behzadmehr3

  • 1Clinical Pharmacy Department, School of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran.

Heart Failure Reviews
|November 21, 2019
PubMed

Insights

This systematic review found that patients with congestive heart failure (CHF) generally experience moderate to poor quality of life (QOL). Regular QOL assessments are crucial for comprehensive CHF patient care.

Area of Science:

  • Cardiology
  • Public Health
  • Health Services Research

Background:

  • Quality of life (QOL) is a critical aspect of patient care in congestive heart failure (CHF).
  • Previous research on QOL in CHF patients consists of individual studies, lacking a comprehensive synthesis.

Purpose of the Study:

  • To conduct a systematic review and meta-analysis to comprehensively assess the QOL of patients with CHF.
  • To identify factors influencing QOL in CHF patients, such as geographical region.

Main Methods:

  • Systematic review and meta-analysis of studies published between January 1, 2000, and December 31, 2018.
  • Searched PubMed, Scopus, and Web of Science databases using keywords 'QOL' and 'heart failure'.
  • Included 70 studies with 25,180 participants; data extraction and quality assessment performed by two independent researchers.

Main Results:

  • The overall mean QOL score was 44.1 (95% CI 40.6, 47.5), indicating moderate to poor QOL.
  • CHF patients in the Americas reported higher QOL scores compared to other regions.
  • Analysis of SF-36 survey data showed an average Physical Component Score (PCS) of 33.3 and Mental Component Score (MCS) of 50.6.

Conclusions:

  • The findings indicate a moderate to poor QOL among CHF patients, necessitating regular monitoring.
  • Periodic QOL measurements using appropriate tools should be integrated into routine CHF patient care.
  • Geographical variations in QOL scores suggest the need for region-specific interventions.

Keywords:
Heart failureMeta-analysisQuality of life

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