Prevalence of heart failure and left ventricular dysfunction in China: the China Hypertension Survey, 2012-2015

Guang Hao1, Xin Wang2, Zuo Chen2

  • 1Department of Epidemiology, School of Medicine, Jinan University, Guangzhou, China.

Insights

Heart failure (HF) is increasingly prevalent in China, affecting 1.3% of adults. Left ventricular dysfunction is common, yet hypertension management in HF patients remains low.

Area of Science:

  • Cardiology
  • Epidemiology
  • Public Health

Background:

  • Heart failure (HF) poses a significant global health challenge.
  • Nationwide epidemiological data on HF in China post-2000 is lacking.
  • Understanding HF prevalence and management is crucial for public health initiatives.

Purpose of the Study:

  • To determine the prevalence of left ventricular (LV) dysfunction and HF in China.
  • To assess HF prevalence across different ejection fraction categories (reduced, mid-range, preserved).
  • To investigate hypertension treatment and control among HF patients in China.

Main Methods:

  • Utilized data from the China Hypertension Survey (CHS) with 22,158 participants.
  • Assessed HF history and cardiovascular diseases via self-report.
  • Employed two-dimensional and Doppler echocardiography for LV dysfunction evaluation.

Main Results:

  • Overall HF prevalence was 1.3% (estimated 13.7 million adults ≥35 years).
  • LV systolic dysfunction affected 1.4%, and moderate/severe LV diastolic dysfunction affected 2.7%.
  • Among hypertensive HF patients, 57.7% received antihypertensive medication, with only 14.5% achieving blood pressure <140/90 mmHg.

Conclusions:

  • HF prevalence has increased in China, with widespread LV dysfunction.
  • Hypertension treatment and control rates in HF patients are notably low.
  • Urgent interventions are needed to improve HF and hypertension management in China.
Abstract

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
633
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.6K
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
410
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
633
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
264
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
2.2K