Association of BMI and lipid profiles with axillary osmidrosis: a retrospective case-control study

Axillary osmidrosis (AO) is a common disease. There are no safely effective therapies for AO.

The objective of our study was to establish whether increased BMI and lipid profiles affects the prevalence of AO.

Our research was a retrospective case-control study. According to our criteria, 203 patients with AO were included in our study and 94 subjects with no bromhidrosis were matched as the control group. Age, ethnicity, living area, level of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TGs), and body mass index (BMI) were obtained from the clinical data. Logistic regression analysis and multivariate Cox regression analysis were used to investigate the association of BMI and lipid profiles with AO.

BMI, TC, and TG LDL were significantly higher in patients with AO compared with control subjects (p<.05). A high BMI (≥24 kg/m²) or overweight, compared with a low BMI (<24 kg/m²) or normal, was associated with an increased risk of AO (OR: 6.1; 95% CI: 2.7, 13.4; p<.0001). Adjustment of the lipid profiles' group has a higher risk of disease than unadjusted (OR: 56.4 compared with 6.1, respectively), while adjusting lipid profiles shows a lower risk than unadjusted (OR: 1.3 compared with 6.1, respectively).

The results of our study revealed that increased BMI is significantly associated with the prevalence of AO.