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Updated: Jan 3, 2026
Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Photo-controlled reversible secondary self-assembly of supramolecular nanosheets and their drug delivery behavior
1MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, P. O. Box 1254, Harbin, 150001, P. R. China. zhangchunhua@hit.edu.cn.
Abstract:
Supramolecular nano-drug delivery systems with stimuli-responsive features have attracted extensive attention in photodynamic therapy. In this work, a new kind of photo-controlled reversible two dimensional (2D) nanosheet was constructed by cucurbit[8]uril (CB[8])-mediated ternary complexation with lanthanide complexes, azobenzene quaternary ammonium salt and sodium dodecyl sulfonate, which exhibited rapid morphological transformation and high drug loading capacities. The constructed supramolecular secondary self-assembly system has become a very promising candidate as a drug nanocarrier.
