Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Personality Psychology01:29

Introduction to Personality Psychology

19.2K
Personality encompasses a set of enduring traits and behavioral patterns that define how individuals think, feel, and interact, ultimately shaping their unique identities. The concept of personality has deep historical roots, deriving from the Latin term "persona," which means "mask." This term initially referred to the roles played by actors in ancient theater, signifying the different facets individuals display in various contexts.
Early Theories of Personality
The study of...
19.2K
Personality Theory by Eysenck and Eysenck01:29

Personality Theory by Eysenck and Eysenck

1.1K
Hans and Sybil Eysenck developed a widely recognized theory of personality, which emphasizes the role of temperament and genetically based differences in shaping individual traits. Their theory posits that biological factors primarily determine personality and can be understood through two main dimensions: extroversion/introversion and neuroticism/stability.
In the extroversion/introversion dimension, highly extroverted people are sociable, outgoing, and easily connect with others. In contrast,...
1.1K
Human Genetics01:28

Human Genetics

1.3K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.3K
Gene-Environment Interactions01:20

Gene-Environment Interactions

1.0K
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
1.0K
Causes of Social Behavior III: Biological and Environmental Influences01:28

Causes of Social Behavior III: Biological and Environmental Influences

194
Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...
194
Five-Factor Theory of Personality01:29

Five-Factor Theory of Personality

1.7K
The five-factor model, often called the Big Five personality traits, is widely accepted in psychology as a comprehensive framework for understanding personality. These five traits — Openness, Conscientiousness, Extraversion, Agreeableness, and Neuroticism — are often remembered using the acronym OCEAN.
Openness reflects creativity, curiosity, and openness to new experiences. Individuals scoring high in openness are imaginative, have a wide range of interests, and are independent...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Co-expression-based models improve eQTL predictions for transcriptome-wide association studies and highlight new schizophrenia-associated genes.

Nature genetics·2026
Same author

Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

Research square·2026
Same author

Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants.

Atherosclerosis·2025
Same author

Brazilian adaptation and validation of the Multidimensional Measure of Parasocial Relationships (MMPR).

Scientific reports·2025
Same author

Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.

Nature communications·2025
Same author

Extending the model of children's conduct problems: A cross-sectional study of the interaction of maternal temperament and character, maternal parenting practices, and their child's effortful control.

PloS one·2025

Related Experiment Video

Updated: Jan 3, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.4K

Three genetic-environmental networks for human personality.

Igor Zwir1,2, Coral Del-Val2, Javier Arnedo2

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

Molecular Psychiatry
|November 22, 2019
PubMed
Summary

Human personality integrates temperament and character via three distinct genetic networks. These networks, linked to specific learning systems, influence health and longevity across diverse populations.

More Related Videos

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.5K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.7K

Related Experiment Videos

Last Updated: Jan 3, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.4K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.5K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.7K

Area of Science:

  • Neuroscience and Genetics
  • Human Personality Research
  • Behavioral Genetics

Background:

  • Human personality is thought to arise from three learning and memory systems: associative conditioning, intentionality, and self-awareness.
  • Distinct gene sets appear to regulate these systems, influencing temperament (habits, reactivity) and character (self-control, values).
  • The integrated organization and development of these personality components remain poorly understood.

Purpose of the Study:

  • To investigate how temperament and character components of personality are jointly organized.
  • To identify genetic networks associated with these integrated personality structures.
  • To examine the relationship between personality networks and distinct learning/memory systems.

Main Methods:

  • Utilized machine learning on three large, independent genome-wide association studies (Finland, Germany, Korea).
  • Analyzed joint phenotypic networks of temperament and character.
  • Mapped associated genetic and environmental networks to phenotypic clusters.

Main Results:

  • Identified three distinct clusters of individuals based on temperament and character profiles.
  • Found largely disjoint genetic and environmental networks associated with each cluster.
  • Discovered that 72% of 972 mapped genes were unique to a single network.
  • Replicated findings across Finnish, German, and Korean samples.

Conclusions:

  • Temperament and character integrate within three largely disjoint networks.
  • These networks are associated with distinct learning and memory systems.
  • Nearly disjoint genetic and environmental influences shape these networks, impacting healthy longevity.