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Related Experiment Video

Updated: Jan 3, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Acute lymphoblastic leukemia presenting with mesenteric ischemia.

Timothy Krill¹, Michelle Baliss², Jenine Zaibaq¹

¹Department of Gastroenterology and Hepatology, The University of Texas Medical Branch, Texas, USA.

Gastroenterology and Hepatology From Bed to Bench

|November 22, 2019

Summary

Malignancy increases blood clot risk. This case report details a rare instance of T-cell acute lymphoblastic leukemia initially presenting as a complete superior mesenteric artery occlusion.

Keywords:

Arterial occlusion Leukemia Mesenteric ischemia

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Area of Science:

Hematology
Vascular Surgery
Oncology

Background:

Malignancy is linked to a hypercoagulable state, increasing thromboembolic event risk.
Cancer-associated prothrombotic states involve complex, multifactorial mechanisms.
Venous thrombosis is more common than arterial thrombosis in cancer patients.

Observation:

A 44-year-old male presented with complete thrombotic occlusion of the superior mesenteric artery.
The patient underwent emergent thrombectomy for the arterial occlusion.
Hematologic analysis confirmed a diagnosis of T-cell acute lymphoblastic leukemia.

Findings:

Arterial occlusion as an initial presentation of acute leukemia is uncommon.
This case represents the first documented instance of superior mesenteric artery occlusion as the primary manifestation of T-cell acute lymphoblastic leukemia.

Implications:

Highlights the diverse and potentially severe vascular complications of hematologic malignancies.
Emphasizes the importance of considering thrombotic events in the differential diagnosis of acute abdominal conditions in leukemia patients.
Underscores the need for prompt diagnosis and intervention in acute mesenteric ischemia, even in the context of newly diagnosed leukemia.