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Toward Progress in Quantitative Translational Medicine: A Call to Action
Karthik Venkatakrishnan1, Songmao Zheng2, Cynthia J Musante3
1Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.
Clinical Pharmacology and Therapeutics
|November 22, 2019
Summary
Quantitative translational medicine (QTM) aims to accelerate drug development. A survey identified key barriers to QTM advancement and proposed solutions for a more efficient, patient-centered approach.
Area of Science:
- Translational medicine
- Drug development
- Quantitative science
Background:
- Quantitative translational medicine (QTM) is crucial for advancing drug discovery and development.
- Bridging the gap between basic research and clinical application requires robust quantitative methods.
Purpose of the Study:
- To identify barriers hindering the progress of Quantitative Translational Medicine (QTM).
- To propose actionable strategies for the successful implementation of QTM.
- To outline a path for QTM through a survey of experts.
Main Methods:
- Conducted a survey by the American Society for Clinical Pharmacology and Therapeutics (ASCPT).
- Collected data on perceived obstacles to QTM advancement.
- Analyzed survey results to identify key themes and challenges.
Main Results:
- Identified significant barriers to the advancement and deployment of QTM.
- Highlighted the need for a structured approach to overcome these obstacles.
- Survey results underscore the multifaceted nature of challenges in QTM.
Conclusions:
- Breaking down barriers requires patient-centered stewardship and effective communication.
- Cross-sector collaboration and a modernized educational curriculum are essential for QTM.
- Implementing these strategies will accelerate the journey from scientific idea to medical application.
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