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Related Concept Videos

Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

934
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

341
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Related Experiment Video

Updated: Jan 3, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

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Transcatheter Aortic Valve Replacement: Procedure and Outcomes.

Erwan Salaun1, Philippe Pibarot1, Josep Rodés-Cabau1

  • 1Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec Heart & Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Québec, Québec G1V-4G5, Canada.

Cardiology Clinics
|November 23, 2019
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) is now suitable for all surgical risk levels, including low-risk patients, showing comparable outcomes to traditional surgery. Long-term valve durability requires further study.

Keywords:
Aortic stenosisInterventional cardiologyOutcomesParavalvular regurgitationStructural valve deteriorationTranscatheter aortic valve replacementTranscatheter heart valve

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Transcatheter aortic valve replacement (TAVR) was initially indicated for severe symptomatic aortic stenosis in patients at prohibitive surgical risk.
  • The application of TAVR has expanded to include patients with high and intermediate surgical risk.
  • Recent trials demonstrate TAVR's noninferiority or superiority compared to surgical aortic valve replacement in low-surgical-risk populations.

Purpose of the Study:

  • To present the evolution and current status of transcatheter aortic valve replacement (TAVR).
  • To review different TAVR devices and procedures.
  • To discuss the outcomes associated with TAVR.

Main Methods:

  • Review of randomized trials and clinical data.
  • Analysis of procedural outcomes and device evolution.
  • Assessment of TAVR's applicability across different surgical risk strata.

Main Results:

  • TAVR has demonstrated improved procedural outcomes.
  • TAVR is now a viable option for patients across all surgical risk categories.
  • Evidence suggests TAVR is noninferior or superior to surgical aortic valve replacement in low-risk patients.

Conclusions:

  • Transcatheter aortic valve replacement (TAVR) has evolved significantly, expanding its use to lower-risk patients.
  • While procedural outcomes are favorable, long-term durability of transcatheter heart valves needs continued evaluation.
  • TAVR represents a major advancement in treating aortic stenosis.