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Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
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Multiple large vessel aneurysmal formation in HIV-infected patients
Ju-Mei Chang1, Hassan Lameen1,2, Garth C Skinner3
1Department of Radiology, Edendale Hospital, South Africa.
SA Journal of Radiology
|November 23, 2019
Summary
A new type of large blood vessel swelling, known as aneurysmal dilatation, is increasingly seen in individuals with human immunodeficiency virus (HIV). Computed tomography angiography is recommended for diagnosing this HIV-related vascular anomaly.
Area of Science:
- Vascular Medicine
- Infectious Diseases
- Radiology
Background:
- Human immunodeficiency virus (HIV) infection is associated with various vascular complications.
- Aneurysmal dilatation of large vessels is an emerging concern in the HIV-positive population.
Observation:
- This report details a case of aneurysmal dilatation in a patient with HIV.
- The case highlights diagnostic challenges encountered in identifying this vascular anomaly.
Findings:
- Computed tomography (CT) angiography is identified as the optimal imaging modality.
- The study emphasizes the importance of advanced imaging for accurate diagnosis.
Implications:
- Increased awareness of HIV-associated aneurysmal dilatation is crucial for clinicians.
- CT angiography should be considered in the diagnostic workup of HIV patients with suspected vascular abnormalities.
- This finding contributes to understanding the spectrum of vascular pathology in HIV infection.
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