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Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
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Multiple large vessel aneurysmal formation in HIV-infected patients

Ju-Mei Chang1, Hassan Lameen1,2, Garth C Skinner3

  • 1Department of Radiology, Edendale Hospital, South Africa.

SA Journal of Radiology
|November 23, 2019
PubMed

Insights

A new type of large blood vessel swelling, known as aneurysmal dilatation, is increasingly seen in individuals with human immunodeficiency virus (HIV). Computed tomography angiography is recommended for diagnosing this HIV-related vascular anomaly.

Area of Science:

  • Vascular Medicine
  • Infectious Diseases
  • Radiology

Background:

  • Human immunodeficiency virus (HIV) infection is associated with various vascular complications.
  • Aneurysmal dilatation of large vessels is an emerging concern in the HIV-positive population.

Observation:

  • This report details a case of aneurysmal dilatation in a patient with HIV.
  • The case highlights diagnostic challenges encountered in identifying this vascular anomaly.

Findings:

  • Computed tomography (CT) angiography is identified as the optimal imaging modality.
  • The study emphasizes the importance of advanced imaging for accurate diagnosis.

Implications:

  • Increased awareness of HIV-associated aneurysmal dilatation is crucial for clinicians.
  • CT angiography should be considered in the diagnostic workup of HIV patients with suspected vascular abnormalities.
  • This finding contributes to understanding the spectrum of vascular pathology in HIV infection.

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