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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Role of Coronary Calcium Score to Identify Candidates for ASCVD Prevention
Hong Loan Nguyen1,2, Jing Liu3,4, Maygen Del Castillo1,2
1Baylor College of Medicine, McNair Campus, 7200 Cambridge St., Suite 8B, Houston, TX, 77030, USA.
Insights
Coronary artery calcium scoring effectively predicts cardiovascular disease risk in asymptomatic individuals. This method aids in risk stratification, guiding interventions and improving prognosis, as recognized by updated guidelines.
Area of Science:
- Cardiology
- Medical Imaging
- Preventive Medicine
Background:
- Coronary artery calcification (CAC) is a marker of atherosclerosis.
- CAC scoring is a reproducible method for cardiovascular disease (CVD) risk assessment.
- Recent guidelines incorporate CAC testing into risk stratification and treatment decisions.
Purpose of the Study:
- To review the mechanism of CAC formation and detection.
- To discuss the implications of CAC in CVD risk stratification.
- To explore CAC's role in guiding intervention and prognosis for asymptomatic individuals.
Main Methods:
- Review of cohort and population studies on CAC scoring.
- Analysis of current ACC/AHA guidelines regarding CAC testing.
- Synthesis of evidence on CAC's impact on CVD management.
Main Results:
- CAC scoring demonstrates effectiveness and reproducibility in predicting CVD risk.
- CAC plays a unique role in influencing therapeutic interventions.
- The prognostic value of CAC in asymptomatic populations is increasingly recognized.
Conclusions:
- CAC scoring is a valuable tool for CVD risk stratification in asymptomatic individuals.
- Understanding CAC mechanisms aids in its clinical application.
- CAC assessment informs treatment strategies and improves patient outcomes.
Purpose Of Review:
In this review, we describe the mechanism behind coronary artery calcification formation and detection, as well as its implication in cardiovascular disease (CVD) risk stratification, intervention, and prognosis in asymptomatic individuals.
Recent Findings:
Multiple cohort and population studies have shown that coronary artery calcium scoring is effective and reproducible in predicting the risk for cardiovascular disease. The updated 2018 ACC/AHA guideline has incorporated consideration of coronary artery calcification testing into cardiovascular disease risk stratification and therapy guidance. Coronary artery calcification's evidence-based role in detection, risk stratification, and ultimately its unique influence on therapeutic intervention and prognosis of cardiovascular disease in asymptomatic population is increasingly being recognized..
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