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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Management of Maternal Stroke and Mitigating Risk
Mariel G Kozberg1, Erica C Camargo2
1Massachusetts General Hospital, 55 Fruit Street, Boston, MA, USA.
Pregnancy increases stroke risk, especially with hypertension. Management of pregnancy-associated stroke should align with non-pregnant care, considering safety for the fetus when selecting treatments.
Area of Science:
- Neurology
- Obstetrics
- Cardiovascular Medicine
Background:
- Pregnancy is a state of increased risk for both hemorrhagic and ischemic strokes.
- Hypertensive disorders of pregnancy are a significant contributing factor to pregnancy-associated strokes.
Purpose of the Study:
- To review the pathophysiological mechanisms of increased stroke risk during pregnancy.
- To discuss management considerations for stroke in pregnant patients.
- To explore strategies for reducing stroke risk in this population.
Main Methods:
- This is a review article, synthesizing existing literature on pregnancy-associated stroke.
- The review discusses pathophysiological mechanisms, clinical management, and risk reduction strategies.
Main Results:
- Pregnancy-associated stroke rates have risen in the last 20 years, linked to hypertensive disorders.
- Evidence supports acute reperfusion therapies like tissue plasminogen activator (tPA) and endovascular thrombectomy for ischemic stroke.
- Stroke management in pregnant individuals should generally follow non-pregnant protocols, with careful selection of secondary prevention agents.
Conclusions:
- Pregnant women face elevated stroke risks due to physiological changes.
- Acute stroke treatment in pregnancy should mirror non-pregnant care, utilizing reperfusion therapies where indicated.
- Secondary stroke prevention requires careful consideration of the pregnancy status.
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