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Modified-Release Drug Delivery Systems: Stimuli-Activated

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...

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Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

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Published on: April 16, 2018

Natural Polymer-based Stimuli-responsive Hydrogels.

Yuheng Jiang^1,2,3,4, Ying Wang¹, Qin Li¹

¹School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, China.

Current Medicinal Chemistry

|November 23, 2019

Summary

This summary is machine-generated.

Intelligent natural polymer hydrogels respond to stimuli, offering advanced medical applications. This review highlights polysaccharide-based hydrogels, detailing their preparation, properties, and medical uses.

Keywords:

Chemical stimuli Natural polymers Polysaccharides Smart hydrogels Stimuli-responsive.

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Area of Science:

Materials Science
Biomedical Engineering
Polymer Chemistry

Background:

Intelligent polymer hydrogels exhibit stimulus-responsive structural and volume changes.
Natural polymer-based hydrogels offer eco-friendliness, abundant sources, and good biocompatibility.
These hydrogels are classified by their responsiveness: temperature, pH, light, electric, redox, enzyme, magnetic, and multi-responsive.

Purpose of the Study:

To review recent advancements in natural polymer-based stimuli-responsive hydrogels.
To focus on hydrogels derived from polysaccharides.
To highlight their preparation methods, properties, and medical applications.

Main Methods:

Literature review of recent studies on natural polymer-based stimuli-responsive hydrogels.
Compilation and analysis of data on polysaccharide-derived hydrogels.
Focus on preparation techniques, characteristic properties, and medical relevance.

Main Results:

Natural polymer hydrogels demonstrate significant potential in advanced technologies, particularly in medicine.
Polysaccharide-based hydrogels are a key focus, showcasing diverse stimuli-responsive behaviors.
Various preparation methods yield hydrogels with tailored properties for specific medical applications.

Conclusions:

Natural polymer-based stimuli-responsive hydrogels, especially those from polysaccharides, are promising for medical innovations.
Their tunable properties and biocompatibility make them suitable for a wide range of healthcare solutions.
Further research into their preparation and application will drive advancements in medical technology.