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The Cooperative Effect between Polybasic Region (PBR) and Polysialyltransferase Domain (PSTD) within Tumor-Target

Guo-Ping Zhou1,2, Si-Ming Liao1, Dong Chen1

  • 1National Engineering Research Center for Non-Food Biorefinery, State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Key Laboratory of Bio-refinery, Guangxi Academy of Sciences, 98 Daling Road, Nanning, 530007, China.

Current Topics in Medicinal Chemistry
|November 23, 2019
PubMed

Keywords:
Neural cell adhesion molecules (NCAM)Phyre2 severPolybasic region (PBR)Polysialic acid (polySia)PolysialylationPolysialyltransferase domain (PSTD)Protein 3D structureST8Sia II (STX)ST8Sia IV (PST)Tumor metastasis.

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