Related Experiment Video
Updated: Jan 3, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
Pediatric Kaposi's sarcoma associated with immune reconstitution inflammatory syndrome
Leandro Silva1, Laura Azurara2, Ana Filipe Monteiro3
1Department of Dermatology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, EPE, Lisboa, Portugal.
Abstract:
Immune reconstitution inflammatory syndrome (IRIS) represents paradoxical immune-mediated inflammation in response to an infecting pathogen, occurring after initiation of antiretroviral therapy (ART), concomitantly with immune system recovery. It has also been described in Kaposi's sarcoma (KS). We report a case of a 9-year-old Guinean girl, who developed Kaposi's sarcoma, following introduction of ART. KS associated with immune reconstitution inflammatory syndrome is rare, especially in children, but with the increased use of ART is becoming more prevalent.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Nephrotic Syndrome I : Introduction
Acute Kidney Injury III: Clinical Manifestations
Endocarditis II: Clinical Features of Infective Endocarditis

