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Updated: Aug 14, 2026

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
[Thrombolysis in acute massive lung embolism]
1Gerinnungs- und Fibrinolyselaboratorium, Kantonsspital, Basel.
Thrombolytic therapy of pulmonary embolism reduces total pulmonary resistance more rapidly than heparin alone. In massive pulmonary embolism this hemodynamic benefit usually outweighs the moderately increased bleeding risk if contra-indications are strictly observed. Practical dosage regimens for streptokinase and urokinase are proposed.
Thrombolytic therapy of pulmonary embolism reduces total pulmonary resistance more rapidly than heparin alone. In massive pulmonary embolism this hemodynamic benefit usually outweighs the moderately increased bleeding risk if contra-indications are strictly observed. Practical dosage regimens for streptokinase and urokinase are proposed.
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