Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

909
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
909
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
Glaucoma: Overview01:25

Glaucoma: Overview

1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Hidden Culprit in Optic Neuritis: Mitochondrial Complex I Deficiency Due to a Novel NDUFS1 Mutation.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2026
Same author

Normative axial length growth references in preterm and term infants for clinical use in early onset glaucoma.

The British journal of ophthalmology·2026
Same author

Persistent Pupillary Membrane with Cataract in a Child with NDP gene mutation.

QJM : monthly journal of the Association of Physicians·2026
Same author

Outcomes of Post-Traumatic Pediatric Endophthalmitis Following 25-Gauge Pars Plana Vitrectomy.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2026
Same author

Assessing the Role of Statins as an Adjunctive Anti-VEGF Therapy for Clinically Significant Macular Edema (CSME) in Type 2 Diabetes Mellitus.

Romanian journal of ophthalmology·2026
Same author

Comparison Between 3D Heads-Up Display System and Standard Operating Microscope in Diabetic Vitrectomy for Tractional Retinal Detachment.

Romanian journal of ophthalmology·2026

Related Experiment Video

Updated: Jan 3, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

8.6K

Optical Coherence Tomography Angiography in Amblyopia.

Savleen Kaur, Simar Rajan Singh, Deeksha Katoch

    Ophthalmic Surgery, Lasers & Imaging Retina
    |November 23, 2019
    PubMed
    Summary

    Amblyopia may stem from issues in the choriocapillaris, the eye's photoreceptor blood supply. This study found reduced choriocapillaris vessel density in amblyopic eyes, correlating with visual acuity.

    More Related Videos

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
    07:44

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

    Published on: July 24, 2020

    3.3K
    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    19.2K

    Related Experiment Videos

    Last Updated: Jan 3, 2026

    Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
    07:23

    Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

    Published on: March 26, 2020

    8.6K
    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
    07:44

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

    Published on: July 24, 2020

    3.3K
    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    19.2K

    Area of Science:

    • Ophthalmology
    • Retinal Imaging
    • Neuroscience

    Background:

    • The posterior segment's role in amblyopia pathogenesis is under investigation.
    • Previous studies have not consistently identified abnormalities in the posterior eye segment.
    • The choriocapillaris, crucial for photoreceptor health, has not been extensively studied in amblyopia.

    Purpose of the Study:

    • To investigate the choriocapillaris in treatment-naïve pediatric amblyopia patients.
    • To assess retinal and choriocapillaris structure using optical coherence tomography angiography (OCTA).
    • To determine if choriocapillaris vessel density is altered in amblyopic eyes.

    Main Methods:

    • Prospective study of 14 treatment-naïve amblyopic children (6-12 years old).
    • Best-corrected visual acuity was measured.
    • Optical coherence tomography angiography (OCTA) was used to image the retina and choriocapillaris.

    Main Results:

    • Choriocapillaris vessel density was significantly lower in amblyopic eyes (39.61%) compared to fellow eyes (44.10%).
    • A positive correlation was observed between choriocapillaris vessel density and visual acuity (r=0.41, P=.03).
    • Mean patient age was 10.26 ± 1.31 years.

    Conclusions:

    • The choriocapillaris may play a role in the pathogenesis of amblyopia.
    • Reduced choriocapillaris vessel density is associated with amblyopia.
    • OCTA imaging provides insights into the vascular contributions to amblyopia.