Related Experiment Video
Updated: Jul 31, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Adult Atypical Teratoid/Rhabdoid Tumor in the Pineal Region: Case Report and Literature Review
Joana Monteiro1, Bruno Santiago1, Rui Manilha1
1Department of Neurosurgery, Hospital Garcia de Orta, Almada, Portugal.
Background:
Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system tumor with a poor prognosis. Its occurrence in the pineal region is extremely rare, with only 6 cases in adults reported so far.
Case Description:
We report on a puerperal woman with an AT/RT in the pineal region. Total tumor resection was performed. Definitive diagnosis was confirmed by the loss of nuclear INI1/SMARCB1 staining. The patient underwent radiotherapy and chemotherapy with no evidence of recurrence at 31 months after surgery.
Conclusions:
This case highlights the importance of immunohistochemistry in the diagnosis of the disease and the importance of an aggressive treatment.
