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[Evaluation of a pharmacist-led intervention on polypharmacy].

Kazuya Ooi1

  • 1Laboratory of Clinical Pharmacology, Department of Pharmaceutical Sciences, Suzuka University of Medical Science.

Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|November 26, 2019
PubMed
Summary
This summary is machine-generated.

Pharmacist-led interventions effectively reduced polypharmacy in elderly patients, decreasing the average number of medications and improving symptom changes. This highlights the crucial role of pharmacists in medication management for older adults.

Keywords:
Blood examinationOlder patientPharmaceutical consultationPharmacistPolypharmacy

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Area of Science:

  • Gerontology
  • Clinical Pharmacy
  • Pharmacoeconomics

Background:

  • Japan faces a rapidly aging population, leading to a rise in multiple chronic conditions (comorbidity) and increased medication use (polypharmacy).
  • Polypharmacy in elderly patients presents significant challenges in medication management and patient safety.
  • Pharmacists play a vital role in optimizing medication use and ensuring patient adherence.

Purpose of the Study:

  • To investigate the impact of pharmacist-led interventions on managing polypharmacy in elderly patients.
  • To assess the effectiveness of pharmaceutical consultations in reducing the number of prescribed medications.
  • To evaluate changes in patient symptoms following pharmacist interventions.

Main Methods:

  • A study involving patients aged 65 and older who received pharmaceutical consultations between September and November 2019.
  • Recording of consultation details, number of medication change proposals, and prescription modifications.
  • Tracking of symptom changes at 4 weeks post-consultation to assess intervention outcomes.

Main Results:

  • 361 elderly patients participated, with most being 80 years or older.
  • Pharmacist consultations led to prescription changes in 96.7% of patients.
  • The average number of medications decreased from 7.2 to 6.0, and polypharmacy (≥6 drugs) reduced from 67.3% to 53.7% of patients. Symptom improvement was observed in 84.5% of patients.

Conclusions:

  • Pharmacist-led interventions are effective in reducing polypharmacy among elderly patients.
  • Regular prescription reviews by pharmacists, incorporating physical checks and test results, can improve medication management quality.
  • Integrating blood test results into pharmaceutical advice enhances the pharmacist's ability to provide tailored recommendations.