[Monoclonal antibodies for severe asthma (review)]

Monoclonal antibodies for severe asthma (review) Abstract. Monoclonal antibodies against central steps in the inflammatory cascade of bronchial asthma offer welcome new treatment options for a selected group of patients with severe asthma. The main challenge for the clinician, however, lies in the selection and workup of potential patients. This review discusses the mechanisms of action and the clinical use of these new biologicals.