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[Insulinoma associated with adrenocorticotropic insufficiency and hypergonadotropic hypogonadism: a case study]
Faten Hadjkacem1, Mahdi Kalthoum1, Dorra Ghorbel1
1Service d'Endocrinologie et Diabétologie de CHU Hédi Chaker, route El-Ain, 3029 Sfax, Tunisie.
Abstract:
Pancreatic insulinoma is a rare, often benign, neuroendocrine tumor which may give rise to life-threatening consequences due to hypoglycemia-related accidents. Adrenal deficiency can also cause hypoglycemia. We report the case of a 68-year old patient hospitalized for recurrent hypoglycaemia. Tests were performed that showed endogenous hyperinsulinism, adrenocorticotropin deficiency and hypergonadotropic hypogonadism. The patient received hydrocortisone without improvement. Five years later topography showed insulinoma. This study highlights the clinical, biological, radiological and therapeutic features of insulinoma as well as laboratory test results and shows that insulinoma can cause adrenocorticotropic deficiency and peripheral hypogonadism.
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