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Study the Role of Nasal Scrap Cytology in Allergic Rhinitis Patients in Rural Population
Puneet Singhvi1, Nitish Baisakhiya2, Gurchand Singh2
1ENT Surgeon, Maitri Hospital, Kota, Rajasthan India.
Summary
Nasal scrape cytology is a specific yet not highly sensitive test for allergic rhinitis. This simple, cost-effective method aids in understanding allergic rhinitis severity by analyzing nasal eosinophils.
Area of Science:
- Otorhinolaryngology
- Allergology
- Cytopathology
Background:
- Allergic rhinitis affects a wide age range and remains a challenge despite advanced diagnostics.
- A simple, cost-effective test is needed to assess allergic rhinitis severity.
Purpose of the Study:
- To evaluate nasal scrape cytology as a simple, cost-effective method for assessing allergic rhinitis severity.
- To investigate the pattern and profile of cells, specifically eosinophils, in allergic rhinitis patients.
Main Methods:
- 100 allergic rhinitis patients and 100 controls underwent nasal scrape cytology.
- Samples from the inferior turbinates were stained (May Gurwald Gimesa) and analyzed for eosinophils under microscopy.
- Eosinophil counts were quantified using a standardized scale.
Main Results:
- Nasal eosinophilia was significantly higher in allergic rhinitis patients compared to controls.
- Study group: 25% Grade 1+, 24% Grade 1/2+, 21% Grade 2+, 22% Grade 0.
- Control group: 80% Grade 0. Sensitivity 54%, Specificity 100%.
Conclusions:
- Nasal scrape cytology is a highly specific (100%) but less sensitive (54%) diagnostic tool for allergic rhinitis.
- The method is a valuable, cost-effective addition for evaluating allergic rhinitis severity.
- Further research may explore enhancing the sensitivity of this technique.
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