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Updated: Jan 3, 2026

Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Self-assembly and self-delivery nanodrug of bortezomib: a simple approach to achieve the trade-off between
Fuli Zhao1, Xiang Liu2, Anjie Dong3
1Department of Polymer Science and Engineering, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China. jhuazhang@tju.edu.cn and CNOOC Tianjin Chemical Research and Design Institute Co., Ltd, Tianjin 300131, China.
Abstract:
Bortezomib, dietary tannic acid and an FDA-approved excipient poloxamer were used as building blocks without any chemical syntheses and modifications to construct a dynamic self-delivery nanodrug with high drug loading, outstanding stability, tunable size and pH-controlled release. This strategy with high druggability, reproducibility and productivity might be desirable and useful for pharmaceutical formulations of bortezomib.
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