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Expected-value bias in routine third-trimester growth scans.

L Drukker1, R Droste2, P Chatelain2

  • 1Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|November 26, 2019
PubMed
Summary
This summary is machine-generated.

Expected-value bias is common in fetal growth scans, affecting measurements of head circumference, abdominal circumference, and femur length. This bias can alter estimated fetal weight, potentially misclassifying fetal growth.

Keywords:
artificial intelligenceascertainment biasdetection biasexpectancy biaseye trackingfetal biometrygrowth scanobserver biasobserver effectultrasound

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Area of Science:

  • Prenatal diagnostics
  • Medical imaging
  • Obstetrics and Gynecology

Background:

  • Operators performing fetal growth scans often know the gestational age, potentially introducing expected-value bias.
  • This bias can influence biometric measurements, impacting accurate fetal growth assessment.
  • Understanding the incidence and impact of this bias is crucial for improving diagnostic accuracy.

Purpose of the Study:

  • To evaluate the incidence of expected-value bias during routine fetal growth scans.
  • To assess the impact of expected-value bias on standard biometric measurements (HC, AC, FL).
  • To quantify the effect of bias on estimated fetal weight and growth classification.

Main Methods:

  • Collected prospectively video recordings of routine ultrasound growth scans with operator eye tracking.
  • Defined expected-value bias as operator focus on measurement box during caliper adjustment.
  • Analyzed 272 third-trimester scans measuring head circumference (HC), abdominal circumference (AC), and femur length (FL).

Main Results:

  • Expected-value bias occurred in 91.4% of saved biometric measurements.
  • Measurements were frequently adjusted towards the expected gestational age (47.7% vs. 19.7%).
  • Bias led to significant discordance in estimated fetal weight (up to 10.1%) and potential misclassification of fetal growth.

Conclusions:

  • Expected-value bias is highly prevalent in routine third-trimester fetal growth scans.
  • This bias significantly alters standard biometric measurements and estimated fetal weight.
  • Awareness and mitigation strategies are needed to improve the reliability of fetal growth assessments.