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Immune responsiveness of irradiated mice reconstituted with complement receptor positive CLR+ or negative

J Pryjma, J Strzyzewska, K Pryjma

    Archivum Immunologiae Et Therapiae Experimentalis
    |January 1, 1979
    PubMed

    Spleen and bone marrow cells depleted of CRL cannot restore immune reactivity of irradiated mice to sheep red blood cells SRBC. The response to anti-SIII, a T-independent antigen does not change when irradiated animals are repopulated with spleen cells or spleen cells depleted of CRL. Spleen cells of 6-day-old mice having low number of CRL, in contrast to spleen cells of adult animals, could not reconstitute irradiated recipients.

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