Multiresponsive Supramolecular Luminescent Hydrogels Based on a Nucleoside/Lanthanide Complex
Qianmin Ma1, Meng Zhang1, Xihan Xu1
1Frontier Science Center for Synthetic Biology, Key Laboratory of Systems Bioengineering (MOE), School of Chemical Engineering and Technology , Tianjin University , Tianjin 300350 , P. R. China.
ACS Applied Materials & Interfaces
|November 26, 2019
Summary
Researchers developed novel luminescent hydrogels using natural nucleosides and lanthanides. These biocompatible materials offer unique optical properties for advanced bioimaging and sensing applications.
Area of Science:
- Materials Science
- Biotechnology
- Supramolecular Chemistry
Background:
- Natural molecule-based supramolecular luminescent hydrogels offer unique optical properties and biocompatibility for biomaterials.
- Lanthanide complexes are promising for creating advanced supramolecular luminescent hydrogels.
- Nucleosides, fundamental components of nucleic acids, can act as ligands for lanthanides.
Purpose of the Study:
- To create a novel luminescent hydrogel assembled from lanthanides and nucleosides.
- To investigate the formation mechanism and properties of these nucleoside-lanthanide hydrogels.
- To explore their potential as stimuli-responsive materials for sensing and smart devices.
Main Methods:
- Complexation of lanthanides with nucleosides in aqueous solutions.
- Hydrogel formation from lanthanide-nucleoside complexes.
- Characterization using mass spectrometry (ESI-TOF, MALDI-TOF), NMR, and FTIR spectroscopy.
- Molecular simulations for mechanism elucidation.
- Systematic study of morphology, mechanical properties, and luminescence.
- Evaluation of stimuli-responsive (pH, temperature, ions) and fluorochromic behavior.
Main Results:
- Successfully assembled luminescent hydrogels from lanthanides and nucleosides.
- Demonstrated characteristic lanthanide luminescence within the hydrogel matrix.
- Confirmed coordination modes and formation mechanisms through spectroscopic and computational methods.
- Observed stimuli-responsive fluorochromic properties to pH, temperature, anions, and cations.
- Showcased potential for designing luminescent switches and detecting specific analytes like Cu2+.
Conclusions:
- Developed a feasible strategy for preparing stimuli-responsive luminescent hydrogels using nucleosides and lanthanides.
- Highlighted the diverse potential of nucleoside-based hydrogels as advanced biomaterials.
- Presented a novel pathway for creating smart optical materials with tunable luminescence.
