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[The incisor of the rat--not only an indicator for disorders of homeostasis]
W Ponsold1, R Günther, E Rosenfeld
1Institut für Industrietoxikologie, Martin-Luther-Universität Halle-Wittenberg.
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|August 1, 1988
Abstract:
In experimental endocrinology and for studies of disturbed homeostasis caused by alterations of mineral metabolism rat incisors are known test model. Recently they will be relevant to interpret effects of xenobiotics. In our experiments we found remarkable correlations between specific organ toxicity (affinity) and histotropic effects in the incisors (enamel or dentine), further variations of the reaction in relation to the time of application.