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Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome
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Diagnosis and Management of Castleman Disease

Jeremy S Abramson

    Journal of the National Comprehensive Cancer Network : JNCCN
    |November 26, 2019
    PubMed

    Insights

    Castleman disease treatment varies by type. HHV8-associated Castleman disease is treated with rituximab, while idiopathic Castleman disease prefers siltuximab. Antiretrovirals are essential for HIV-positive patients.

    Area of Science:

    • Hematology
    • Oncology
    • Immunology

    Background:

    • Castleman disease is a rare, nonmalignant lymphoproliferative disorder.
    • Key distinctions include unicentric vs. multicentric presentation, pathological subtypes (hyaline vascular, plasmacytic, mixed), and HHV8-association (often HIV-positive) versus idiopathic forms.

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