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Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator

Yusuke Sasaki1,2, Sana Raza-Iqbal1, Toshiya Tanaka1

  • 1Laboratories for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, Tokyo 153-8904, Japan.

International Journal of Molecular Sciences
|November 27, 2019
PubMed
Summary

Pemafibrate, a selective PPARα modulator, effectively treats high triglycerides and low HDL-C. It enhances fatty acid metabolism and shows anti-inflammatory effects, benefiting patients with dyslipidemia and diabetic complications.

Keywords:
ASCVDEndMTSPPARMαfatty acid β-oxidationketogenesispemafibrate

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