Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

Paul S Kwon1,2,3, Shaokang Ren1, Seok-Joon Kwon4

  • 1Key Laboratory for Organic Electronics and Information Displays and Jiangsu, Key Laboratory for Biosensors, Institute of Advanced Materials, National Synergetic Innovation Center for Advanced Materials, Nanjing University of Posts and Telecommunications, Nanjing, China.

Nature Chemistry
|November 27, 2019
PubMed
Summary

Scientists designed a DNA nanostructure to precisely arrange aptamers, creating a potent dengue virus inhibitor and sensor. This platform shows promise for combating other pathogens.

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