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Comparative Transcriptomics of Ex Vivo, Patient-Derived Endothelial Cells Reveals Novel Pathways Associated With

Joshua A Beckman1, Sean P Doherty1, Zachary B Feldman1

  • 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

JACC. Basic to Translational Science
|November 27, 2019
PubMed

Keywords:
BSA, bovine serum albuminEC, endothelial cellEDTA, ethylenediamine tetra-acetic acidFACS, fluorescence activated cell sortingFDR, false discovery rateGSEA, gene set enrichment analysisHUVEC, human umbilical vein endothelial cellIV, intravenousPBS, phosphate buffered salineSeq, sequencingT2DM, type 2 diabetes mellitusTGFβ, transforming growth factor betaVEGF, vascular endothelial growth factorVUMC, Vanderbilt University Medical CenterWBC, white blood cellddCt, delta-delta cycle thresholddiabetes mellitusendothelial cell dysfunctionendothelial cellsgene expressionqPCR, quantitative polymerase chain reaction

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