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Does parity affect pregnancy outcomes in the elderly gravida?
Gil Shechter-Maor1,2, Dana Sadeh-Mestechkin3,4, Yael Ganor Paz3,4
1Department of Obstetrics and Gynecology, Meir Medical Center, Tel Aviv University, Tchernichovsky 59, 4428164, Kfar Saba, Israel. gilshec@gmail.com.
First-time mothers aged 35 and older face higher risks for pregnancy complications like preterm delivery and hypertensive disorders. These risks are elevated compared to multiparous women, highlighting the impact of late first-time childbirth on maternal health outcomes.
Area of Science:
- Maternal-Fetal Medicine
- Reproductive Health
- Obstetrics
Background:
- Advanced maternal age (35 years and older) is associated with increased pregnancy risks.
- Understanding the specific risks for first-time mothers in this age group is crucial for targeted prenatal care.
Purpose of the Study:
- To compare maternal complications in older primiparas (first-time mothers) versus multiparous women (those who have had previous births) delivering at age 35 or older.
- To determine if being a first-time mother at an advanced reproductive age contributes independently to adverse pregnancy outcomes.
Main Methods:
- Retrospective analysis of electronic medical records from a high-volume academic medical center.
- Multivariate logistic regression was employed to assess the impact of parity on maternal complications, adjusting for confounding factors.
Main Results:
- Older primiparas exhibited significantly higher rates of twin pregnancy (1.9% vs. 0.8%), preterm delivery before 34 weeks (6.1% vs. 2.9%), hypertensive disorders (3.9% vs. 1.7%), diabetes (4.6% vs. 3.2%), and intrauterine growth restriction (IUGR) (10.5% vs. 4.7%) compared to multiparous women.
- These increased risks for primiparas persisted after adjusting for baseline characteristics and medical history.
Conclusions:
- Pregnancy complications typically associated with older maternal age are more prevalent in first-time mothers delivering at age 35 or older.
- Both advanced maternal age and first-time childbirth in later reproductive years are significant contributors to adverse pregnancy outcomes.
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